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Semax

Semax

Cognitive

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€34per vial12% OFF

💰 Buy the pack of 10 for €189 — save 44%

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Add Bacteriostatic Water?

Required for reconstituting lyophilized peptides

99%+ Purity

Third-Party Tested

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⚠️ RESEARCH USE ONLY

Strictly for laboratory research purposes. Not intended for human consumption.

Overview

Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the ACTH(4–10) fragment. Originally developed in Russia, it is a well-characterized neuropeptide with potent nootropic, neuroprotective, and BDNF-stimulating properties. It has been approved in Russia for stroke and cognitive enhancement applications.

Mechanism of Action

  • ▸Stimulates BDNF (brain-derived neurotrophic factor) and NGF synthesis
  • ▸Activates ACTH and MSH receptors in the brain
  • ▸Enhances dopaminergic and serotonergic neurotransmission
  • ▸Reduces excitotoxic neuronal death following ischemia
  • ▸Upregulates VEGF for neuroprotective angiogenesis
  • ▸Modulates HPA axis stress response

Key Research Findings

  • ▸Significant neuroprotection in stroke and traumatic brain injury models
  • ▸Improved memory, attention, and learning in cognitive research studies
  • ▸Up to 800% increase in BDNF expression in hippocampal tissue
  • ▸Anxiolytic effects without sedation in anxiety models
  • ▸Immune-modulating properties — enhancement of T-cell activity
  • ▸Accelerated stroke recovery in clinical settings (Russia)

Research Applications

Semax is used in neuroscience research, cognitive enhancement studies, stroke recovery research, BDNF biology, and anxiety/stress modulation studies.

Reconstitution

Add 1–2 mL bacteriostatic water. Swirl gently until dissolved.

Storage

Lyophilized: –20°C for up to 24 months. Reconstituted: 2–8°C for up to 14 days.

Purity & Testing

≥99% by HPLC · Sequence confirmed · Third-party tested

⚠️ Research Use Only

All information provided is for scientific research purposes only. This product is not intended for human consumption, medical use, diagnosis, or treatment. For use by qualified researchers only. By purchasing, you confirm compliance with all applicable laws and regulations.