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TB500(Thymosin B4 Acetate)

TB500(Thymosin B4 Acetate)

Healing

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€36per vial15% OFF

💰 Buy the kit of 10 for €199 — save 45%

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Add Bacteriostatic Water?

Required for reconstituting lyophilized peptides

99%+ Purity

Third-Party Tested

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⚠️ RESEARCH USE ONLY

Strictly for laboratory research purposes. Not intended for human consumption.

Overview

TB-500 (Thymosin Beta-4) is a synthetic version of the naturally occurring 43-amino acid peptide Thymosin Beta-4 (Tβ4), one of the most abundant and versatile intracellular peptides in mammalian cells. It plays a central role in cellular migration, angiogenesis, tissue repair, and inflammation regulation.

Mechanism of Action

  • ▸Sequesters G-actin monomers, promoting cytoskeletal reorganization and cell migration
  • ▸Upregulates integrin-linked kinase (ILK) for endothelial migration and tube formation
  • ▸Promotes angiogenesis by stimulating VEGF receptor expression
  • ▸Anti-apoptotic: reduces cell death in ischemic tissue
  • ▸Down-regulates NF-κB to reduce inflammatory cytokines
  • ▸Stimulates stem cell differentiation toward cardiac and neural lineages

Key Research Findings

  • ▸Accelerated healing of cardiac muscle following myocardial infarction models
  • ▸Enhanced peripheral nerve regeneration and neuroprotection
  • ▸Promotes healing of skeletal muscle, ligaments, and tendons
  • ▸Reduces inflammation and fibrosis in animal injury models
  • ▸Hair follicle stimulation via activation of hair stem cells
  • ▸Neuroprotection documented in stroke and traumatic brain injury models

Research Applications

TB-500 is used in regenerative medicine, cardiology, neurology, sports science injury research, and inflammatory disease models. Frequently studied in combination with BPC-157 for synergistic tissue repair.

Reconstitution

Add 2 mL bacteriostatic water. Swirl gently — avoid agitation. Allow 5–10 minutes for complete dissolution.

Storage

Lyophilized: –20°C, up to 24 months. Reconstituted: 2–8°C for up to 28 days.

Purity & Testing

≥99% by HPLC · Mass confirmed · Third-party CoA on request

⚠️ Research Use Only

All information provided is for scientific research purposes only. This product is not intended for human consumption, medical use, diagnosis, or treatment. For use by qualified researchers only. By purchasing, you confirm compliance with all applicable laws and regulations.