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Thymosin Alpha-1

Thymosin Alpha-1

Immune

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💰 Buy the kit of 10 for €289 — save 44%

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Add Bacteriostatic Water?

Required for reconstituting lyophilized peptides

99%+ Purity

Third-Party Tested

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⚠️ RESEARCH USE ONLY

Strictly for laboratory research purposes. Not intended for human consumption.

Overview

Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide derived from prothymosin alpha, naturally produced by the thymus gland. It is a potent immunomodulator that has been approved in over 35 countries (as Zadaxin®) for treatment of hepatitis B, hepatitis C, and as an adjuvant in cancer and vaccine protocols.

Mechanism of Action

  • Activates Toll-like receptor 9 (TLR9) to enhance innate immune response
  • Stimulates dendritic cell maturation and antigen presentation
  • Enhances T-helper cell (Th1) differentiation and activity
  • Promotes NK cell and cytotoxic T-lymphocyte activity
  • Upregulates MHC class I/II expression on antigen-presenting cells
  • Regulates apoptosis in cancer cells via p53 pathway activation

Key Research Findings

  • Significantly enhanced viral clearance in HBV and HCV models
  • Improved vaccine response in immunocompromised subjects
  • Demonstrated anti-tumor activity and enhanced chemotherapy response
  • Reduced mortality in sepsis and critical illness models
  • Restoration of immune function in HIV and aging models
  • Used clinically for 30+ years with excellent safety record

Research Applications

Thymosin Alpha-1 is used in immunology research, virology, cancer immunotherapy studies, vaccine adjuvant research, and aging immune system studies.

Reconstitution

Add 1–2 mL bacteriostatic water. Swirl gently until fully dissolved.

Storage

Lyophilized: –20°C for up to 24 months. Reconstituted: 2–8°C for up to 21 days.

Purity & Testing

≥99% by HPLC · Endotoxin tested · Third-party CoA available

⚠️ Research Use Only

All information provided is for scientific research purposes only. This product is not intended for human consumption, medical use, diagnosis, or treatment. For use by qualified researchers only. By purchasing, you confirm compliance with all applicable laws and regulations.